产品货号：
Z17332
中文名称：
GIT2抗体
英文名称：
Anti-GIT2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GIT2 Antibody |
| 指标别名 | GIT2;KIAA0148;ARF GTPase-activating protein GIT2;ARF GAP GIT2;Cool-interacting tyrosine-phosphorylated protein 2;CAT-2;CAT2;G protein-coupled receptor kinase-interactor 2;GRK-interacting protein 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | GIT2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GIT2 recombinant protein (Position:D400-S556). |
| 实际分子量 | 85KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ARF GTPase-activating protein GIT2 is an enzyme that in humans is encoded by the GIT2 gene.This gene encodes a member of the GIT protein family,which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity.GIT proteins traffic between cytoplasmic complexes,focal adhesions,and the cell periphery,and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins.GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking.This gene has been shown to repress lamellipodial extension and focal adhesion turnover,and is thought to regulate cell motility.This gene undergoes extensive alternative splicing to generate multiple isoforms,but the full-length nature of some of these variants has not been determined.The various isoforms have functional differences,with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. |
| Uniprot ID | Q14161 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | GIT ArfGAP 2 |
| 蛋白名全称 | ARF GTPase-activating protein GIT2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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